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What are the best aromatase inhibitors? In studies of previously treated postmenopausal women with metastatic disease, the aromatase inhibitors were typically at least as effective as megestrol or tamoxifen. Anastrozole and letrozole both demonstrated improved survival compared with megestrol, and greater overall (complete and partial) response.
What is second line medication? Second line drugs are the TB drugs that are used for the treatment of drug resistant TB. The second line drugs include Levofloxacin or Moxifloxacin, Bedaquiline and Linezolid.
Is tamoxifen a cytotoxic drug? In conclusion, tamoxifen exhibits cytotoxic effects in MCF7 breast cancer cells. The effect of tamoxifen on apoptosis was shown as an increase in caspase-9 activity at a concentration of 5 Вµg/mL and IC 50 of 4.506 Вµg/mL.
What is a chronic disease mean? Chronic diseases are defined broadly as conditions that last 1 year or more and require ongoing medical attention or limit activities of daily living or both. Chronic diseases such as heart disease, cancer, and diabetes are the leading causes of death and disability in the United States.
What is endocrine therapy for breast cancer? Hormone therapy, also called endocrine therapy, adds, blocks, or removes those chemicals to treat the disease. There are two types of hormone therapy for breast cancer : Drugs that stop estrogen and progesterone from helping breast cancer cells grow. Drugs or surgery to keep the ovaries from making the hormones.
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