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Is allopurinol hard on the kidneys? Allopurinol Safe Even With Chronic Kidney Disease. Allopurinol is a safe and effective therapy for lowering urate levels in gout, even in patients with creatinine clearances (CrCL) < 30 mL/min. High doses of allopurinol are rarely needed to achieve acceptable urate levels in patients with chronic kidney disease.
Can you take colchicine with NSAIDs? High dose oral colchicine (1.2 mg followed by 0.6 mg every hour for 6 doses) is generally poorly tolerated because of GI side effects. Lower doses are much better received and may be used in combination with NSAIDs.
Are NPs able to practice independently in the state? State practice and licensure laws restrict the ability of NPs to engage in at least one element of NP practice. State law requires career-long supervision, delegation or team management by another health provider in order for the NP to provide patient care.
What is colchicine made of? Colchicine is an ancient drug is made from the Autumn Crocus, Colchicum autumnale (a poisonous European flowering plant). It has been primarily used in the treatment of gout.
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